CYP3A4 Inhibitors and Nilotinib
cyp3a4 inhibitors and nilotinib Specific and up to date information about Nilotinib. Skip to Content. ... Dosage Adjustments With Coadministration of Strong CYP3A4 Inhibitors Adults.
Drugs known to prolong the QT interval and strong CYP3A4 inhibitors should be avoided. ... Nilotinib exposure is increased in patients with impaired hepatic function ...
• Avoid use of concomitant drugs known to prolong the QT interval and strong CYP3A4 inhibitors ... class of drugs known as kinase inhibitors. Nilotinib drug ...
Avoid use of concomitant drugs known to prolong the QT interval and strong CYP3A4 inhibitors
CYP3A4 Inhibitors and Nilotinib
(5.7). ... Nilotinib is a competitive inhibitor of CYP3A4, ...
Sudden deaths have been reported in patients receiving nilotinib (5.3). ... Drugs known to prolong the QT interval and strong CYP3A4 inhibitors should be ...
Drugs known to prolong the QT interval and strong CYP3A4 inhibitors ... and titanium dioxide. 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of Action Nilotinib is an inhibitor ...
Information from the FDA about the approval of nilotinib and the clinical trials that ... Drugs known to prolong the QT interval and strong CYP3A4 inhibitors should be ...
TASIGNA should not be taken with CYP3A4 inhibitors or inducers; ... Nilotinib exposure is increased in patients with impaired hepatic function.
Due to the possibility of drug interaction, administration of nilotinib along with CYP3A4 inhibitors or drugs that prolong QT interval is not advised.
concomitant strong CYP3A4 Inhibitors and Nilotinib CYP3A4 inhibitors or grapefruit products: avoid if possible; if use is necessary, stop nilotinib; ... (msec): stop nilotinib; ...
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